Semaglutide Therapy

There is a class of type 2 diabetes drugs that not only improves blood sugar control but may also lead to weight loss. This class of drugs is commonly called glucagon-like peptide 1 (GLP-1) agonists. One of these drugs is semaglutide. Weight loss can vary depending on which GLP-1 drug is used and the dose of medication. Studies have found that people using semaglutide along with making lifestyle changes lost about 33.7 pounds (15.3 kilograms) versus 5.7 pounds (2.6 kilograms) in those who didn't use the drug.
 

How Does Semaglutide Work?

  1. Semaglutide increases the amount of insulin produced by your body, which then reduces the level of sugar in the blood. Semaglutide is used most often as a diabetes medication.
  2. It reduces the amount of a substance called glucagon being produced by the pancreas. Glucagon causes the liver to produce more sugar, so by reducing the amount of glucagon in the body, this also helps to reduce the levels of sugar in the blood.
  3. It works on the stomach so that food passes more slowly through it. This means that the sugar from meals takes longer to get into the blood.
  4. Weight loss is thought to be achieved through a variety of mechanisms, including the delayed stomach emptying, increased satiety or fullness, increased resting energy expenditure, as well as the direct influence of the appetite center of the brain.

How Is Semaglutide Administered

Semaglutide is a liquid that is injected under the skin weekly. At the first visit, patients are instruced on how to self-adminter the medication so that injections can be done at home. 

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